Current Pain and Headache Reports

, Volume 16, Issue 2, pp 180–184

Oral Triptans in the Preventive Management of Cluster Headache

Trigeminal Autonomic Cephalalgias (M Matharu, Section Editor)

DOI: 10.1007/s11916-012-0251-5

Cite this article as:
Pageler, L. & Limmroth, V. Curr Pain Headache Rep (2012) 16: 180. doi:10.1007/s11916-012-0251-5


Cluster headache is a rare primary neurovascular headache and a severe pain condition with unilateral headache over 15–180 minutes and concomitant unilateral autonomic symptoms. The detailed pathophysiology of the condition is still unclear. Only a few evidence-based therapeutic options for acute therapy and the preventive management of the disease are available. Triptans, in particular sumatriptan 6 mg subcutaneously, are highly effective for acute treatment. This review focuses on the potential use of oral triptans in the prophylaxis of cluster headache.


Cluster Headache Triptans Prophylaxis Guidelines Controlled trials Pharmacotherapy Trigeminal autonomic cephalalgias Clinical trials 

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of Neurology, Cologne City HospitalsUniversity of CologneCologneGermany

Personalised recommendations