Current Pain and Headache Reports

, Volume 14, Issue 4, pp 256–260

Musculoskeletal Pain Associated With Corticosteroid Therapy in Cancer


DOI: 10.1007/s11916-010-0120-z

Cite this article as:
Frieze, D.A. Curr Pain Headache Rep (2010) 14: 256. doi:10.1007/s11916-010-0120-z


Corticosteroids have multiple uses in the care of the cancer patient. Although they confer benefit to the patient, high doses and extended duration of use may lead to significant adverse effects. Adverse effects such as osteoporosis-induced fractures, osteonecrosis, myopathy and myalgias can cause significant pain and have a negative impact on the patient’s quality of life. In this paper, I will review the mechanisms involved in the toxicity, risk factors, prevalence, prevention, and treatment strategies.


Musculoskeletal pain Corticosteroid therapy Cancer Osteoporosis Osteonecrosis Myopathy Myalgia 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.University of Washington Medical CenterSeattleUSA

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