Current Pain and Headache Reports

, Volume 12, Issue 2, pp 122–127

Medication-overuse headache in patients with cluster headache

Article

Abstract

Cluster headache (CH) is associated with the most severe pain of the primary headache disorders. Barriers to optimal care include misdiagnosis, diagnostic delay, undertreatment, and mismanagement. Medication-over-use headache (MOH) may further complicate CH and may present as increased CH frequency or development of a background headache, which may be featureless or have some migrainous quality. A personal or familial history of migraine appears to be strongly associated with the development of MOH in CH, at least with the phenotype of background headache. Patients with CH, especially those with a personal and/or family history of migraine, must be carefully monitored for MOH, and medication withdrawal should be considered if a CH patient presents with features of MOH.

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Copyright information

© Current Medicine Group LLC 2008

Authors and Affiliations

  • Koen Paemeleire
    • 1
  • Stefan Evers
  • Peter J. Goadsby
  1. 1.Headache Clinic, Department of NeurologyGhent University HospitalGhentBelgium

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