Current Pain and Headache Reports

, Volume 11, Issue 3, pp 208–214

Update on pharmacotherapy guidelines for treatment of neuropathic pain


DOI: 10.1007/s11916-007-0192-6

Cite this article as:
Wallace, J.M. Curr Pain Headache Rep (2007) 11: 208. doi:10.1007/s11916-007-0192-6


Neuropathic pain encompasses a myriad of painful disease states that are often hard to treat, especially with one single medication. In the comprehensive treatment of neuropathic pain, the concept of complex polypharmacy is a rational approach, accompanied by physical and mental health therapies. Medications primarily used for neuropathic pain generally fall into the categories of anticonvulsants, antidepressants, opioids, and topical agents. Generally, most first-line medications used today show a response rate of approximately 30% to 50% reduction in pain in up to 50% of patients treated. There is no “gold standard” in regard to one medication for neuropathic pain. Some new medications have emerged during the past few years that help to augment the armamentarium of medications used in neuropathic pain. This paper reviews the definition of neuropathic pain and introduces the reader to the evidence-based literature on these new medications available for the treatment of neuropathic

Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  1. 1.George E. Whalen VA Medical CenterSalt Lake CityUSA

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