The management of pain in arthritis and the use of cyclooxygenase-2 inhibitors: New paradigms and insights
Chronic pain from arthritis has been one of the biggest causes of disability and loss of function in the United States. This is still the case despite many new insights into the pathophysiology of pain, effective treatment approaches, and new safer medications that can be used for long-term use. There are many different types of arthritic problems. New diseasemodifying agents that are available for some of these types of arthritic diseases such as rheumatoid arthritis have the potential to have a substantial impact on improvement in the long-term prognosis. Despite this optimistic outlook, pain often is a significant problem and should be treated whenever it becomes a barrier to function.
KeywordsMeloxicam Etodolac Nabumetone Valdecoxib Diflunisal
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References and Recommended Reading
- 7.Ross E: Hot Topics in Pain Management, edn 1. Philadelphia: Hanley and Belfus; 2004:452. This is a comprehensive guide to managing pain of all types. Medication management for pain is covered in chapters 3 and 4 and an arthritis overview is covered in chapter 13.Google Scholar
- 16.American Pain Society: Guideline for the Management of Pain in Osteoarthritis, Rheumatoid Arthritis, and Juvenile Chronic Arthritis, edn 1. Glenview: American Pain Society; 2002:178. This is the latest consensus guideline regarding medication management for arthritis. The key feature of this monograph is a change in opinion suggesting that COX medications are preferred before the use of mixed NSAIDs for long-term use.Google Scholar