Current Review of Pain

, Volume 4, Issue 6, pp 451–458 | Cite as

Nociceptors for the 21st Century

  • Francisco J. Alvarez
  • Robert E. W. Fyffe


This review summarizes recent developments in the context of the neurochemical classification of nociceptors and explores the relationships between functionally and neurochemically defined subgroups. Although the complete picture is not yet available, several lines of intriguing evidence suggest that despite the complexity and diversity of nociceptor properties, a relatively “simple” neurochemical classification fits well with several recently identified molecular characteristics.


Nerve Growth Factor Dorsal Root Ganglion Capsaicin Sensory Neuron Dorsal Root Ganglion Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Science Inc 2000

Authors and Affiliations

  • Francisco J. Alvarez
    • 1
  • Robert E. W. Fyffe
    • 1
  1. 1.Department of AnatomySchool of Medicine, Wright State UniversityDaytonUSA

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