Current Osteoporosis Reports

, Volume 16, Issue 4, pp 512–518 | Cite as

Surgical Approach to Bone Metastases

  • Geoffrey W. Siegel
  • J. Sybil Biermann
  • Anda-Alexandra Calinescu
  • Daniel E. Spratt
  • Nicholas J. SzerlipEmail author
Cancer-induced Musculoskeletal Diseases (J Sterling and E Keller, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Cancer-induced Musculoskeletal Diseases


Purpose of Review

The purpose of this review was to examine the recent changes in the surgical treatment of bone metastases and how the treatment paradigm has shifted with the improvement of adjuvant therapies. How surgery fits into the local and systemic treatment was reviewed for bone metastases in different areas.

Recent Findings

The more common use of targeted chemotherapies and focused high-dose radiation have altered the treatment paradigm of bone metastases.


Overall changes in the surgical treatment of bone metastases have been driven by an increased multidisciplinary approach to metastatic cancer and the awareness that one type of surgery does not work for all patients. The individual patient treatment goals dictate the surgical procedures used to achieve these goals. Advancements in adjuvant therapy-like radiation and more targeted chemotherapies have allowed for less invasive surgical approaches and therefore faster recoveries and reduced surgical morbidity for patients.


Bone metastases Spinal metastases Pain Surgery Cancer 


Compliance with Ethical Standards

Conflict of Interest

Geoffrey Siegel, J. Sybil Biermann, Anda-Alexandra Calinescu, Daniel Spratt, and Nicholas Szerlip declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Financial Support and Industry Affiliations Pertinent to This Manuscript

No disclosures or financial support to report for any authors that is pertinent to this manuscript.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major Importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Geoffrey W. Siegel
    • 1
    • 2
  • J. Sybil Biermann
    • 1
  • Anda-Alexandra Calinescu
    • 3
  • Daniel E. Spratt
    • 4
  • Nicholas J. Szerlip
    • 2
    • 3
    Email author
  1. 1.Department of Orthopaedic SurgeryUniversity of MichiganAnn ArborUSA
  2. 2.Veterans Affairs Medical CenterAnn ArborUSA
  3. 3.Department of NeurosurgeryUniversity of MichiganAnn ArborUSA
  4. 4.Department of Radiation OncologyUniversity of MichiganAnn ArborUSA

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