Current Osteoporosis Reports

, Volume 15, Issue 5, pp 473–482 | Cite as

Effects of Excessive Dietary Phosphorus Intake on Bone Health

  • Colby J. Vorland
  • Elizabeth R. Stremke
  • Ranjani N. Moorthi
  • Kathleen M. Hill Gallant
Nutrition, Exercise and Lifestyle in Osteoporosis (S Shapses and J Lappe, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Nutrition, Exercise, and Lifestyle in Osteoporosis


Purpose of Review

The purpose of this review is to provide an overview of dietary phosphorus, its sources, recommended intakes, and its absorption and metabolism in health and in chronic kidney disease and to discuss recent findings in this area with a focus on the effects of inorganic phosphate additives in bone health.

Recent Findings

Recent findings show that increasing dietary phosphorus through inorganic phosphate additives has detrimental effects on bone and mineral metabolism in humans and animals. There is new data supporting an educational intervention to limit phosphate additives in patients with chronic kidney disease to control serum phosphate.


The average intake of phosphorus in the USA is well above the recommended dietary allowance. Inorganic phosphate additives, which are absorbed at a high rate, account for a substantial and likely underestimated portion of this excessive intake. These additives have negative effects on bone metabolism and present a prime opportunity to lower total phosphorus intake in the USA. Further evidence is needed to confirm whether lowering dietary phosphorus intake would have beneficial effects to improve fracture risk.


Phosphorus Nutrition Bone Phosphate additives 


Compliance with Ethical Standards

Conflict of Interest

Kathleen Hill Gallant and Ranjani Moorthi report grants from the NIH (NIDDK K01 DK102864), during the conduct of the study.

Elizabeth Stremke and Colby Vorland declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Colby J. Vorland
    • 1
  • Elizabeth R. Stremke
    • 1
  • Ranjani N. Moorthi
    • 2
  • Kathleen M. Hill Gallant
    • 1
    • 2
  1. 1.Department of Nutrition SciencePurdue UniversityWest LafayetteUSA
  2. 2.Department of Medicine-Division of NephrologyIndiana University School of MedicineIndianapolisUSA

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