Current Osteoporosis Reports

, Volume 14, Issue 2, pp 43–48 | Cite as

Bone and Celiac Disease

  • María Belén Zanchetta
  • Vanesa Longobardi
  • Julio César Bai
Secondary Causes of Osteoporosis (SJ Warden, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Secondary Causes of Osteoporosis

Abstract

More than 50 % of untreated patients with celiac disease (CD) have bone loss detected by bone densitometry (dual-energy X-ray absorptiometry:DXA). Moreover, patients with CD are more likely to have osteoporosis and fragility fractures, especially of the distal radius. Although still controversial, we recommend DXA screening in all celiac disease patients, particularly in those with symptomatic CD at diagnosis and in those who present risk factors for fracture such as older age, menopausal status, previous fracture history, and familial hip fracture history. Bone microarchitecture, especially the trabecular network, may be deteriorated, explaining the higher fracture risk in these patients. Adequate calcium and vitamin D supplementation are also recommended to optimize bone recovery, especially during the first years of gluten free diet (GFD). If higher fracture risk persists after 1 or 2 years of GFD, specific osteoactive treatment may be necessary to improve bone health.

Keywords

Celiac disease Bone disorders Gluten-free diet Bone microarchitecture HRp-QCT Osteoporosis Fractures 

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • María Belén Zanchetta
    • 1
    • 2
  • Vanesa Longobardi
    • 1
    • 2
  • Julio César Bai
    • 3
  1. 1.IDIM, Instituto de Diagnóstico e Investigaciones MetabólicasBuenos AiresArgentina
  2. 2.Cátedra de Osteología y Metabolismo MineralUniversidad del SalvadorBuenos AiresArgentina
  3. 3.Sección Intestino Delgado, Departamento de Medicina, Hospital de Gastroenterología ¨Dr. C. Bonorino Udaondo¨ and Cátedra de Gastroenterología Facultad de MedicinaUniversidad del SalvadorBuenos AiresArgentina

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