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Current Oncology Reports

, 20:62 | Cite as

Peritoneal Metastases from Gastrointestinal Cancer

  • Paul H. Sugarbaker
Gastrointestinal Cancers (J Meyer, Section Editor)
  • 326 Downloads
Part of the following topical collections:
  1. Topical Collection on Gastrointestinal Cancers

Abstract

Purpose of Review

Peritoneal metastases may occur from a majority of cancers that occur within the abdomen or pelvis. When cancer spread to the peritoneal surfaces is documented, a decision regarding palliation vs. an aggressive approach using cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy must be made. The perioperative chemotherapy may be hyperthermic intraperitoneal chemotherapy (HIPEC) administered in the operating room or early postoperative intraperitoneal chemotherapy (EPIC) administered in the first 4 or 5 postoperative days.

Recent Findings

This decision is dependent on a well-defined group of prognostic indicators. In addition to treatment, the clinical and pathologic features of a primary cancer can be used to select perioperative treatments that may prevent cancer cells within the abdomen and pelvis from progressing to established peritoneal metastases. In some clinical situations with appendiceal and colorectal cancers, the clinical or histopathologic features may indicate that second-look surgery plus perioperative chemotherapy should occur.

Summary

Peritoneal metastases should always be considered for treatment or prevention.

Keywords

Peritoneal metastases Appendiceal cancer Malignant peritoneal mesothelioma Colon cancer Recurrent ovarian cancer Gastric cancer Cancer prevention 

Notes

Compliance with Ethical Standards

Conflict of Interest

Paul H. Sugarbaker declares that he has no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Center for Gastrointestinal MalignanciesMedStar Washington Hospital CenterWashingtonUSA

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