Current Oncology Reports

, Volume 9, Issue 5, pp 373–377 | Cite as

Therapy-related acute myelogenous leukemia and myelodysplastic syndrome



Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (t-AML/MDS) are increasing in prevalence with aging of the population and improved survival of patients treated with chemotherapy or radiotherapy for other malignancies. Research focused on the pathogenesis of t-AML/MDS will provide insight into the pathogenesis of de novo AML/MDS. Participation in clinical trials should be encouraged for this patient population because results with available treatment options are clearly suboptimal.


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Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  1. 1.Department of LeukemiaThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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