Current Oncology Reports

, Volume 5, Issue 6, pp 482–485

Surgery for elderly patients with ovarian cancer

  • Martin G. A. Bäuerle
  • Rolf Kreienberg
  • Tanja Volm
Article

Abstract

The stage and tumor remnants after radical surgery are the most important prognostic factors in patients with ovarian cancer. Because the incidence of ovarian cancer is highest in elderly women, and mostly advanced stages occur, radical surgery is necessary in this population as well as in younger patients. Age and the surgeon’s expertise are the factors that influence the quality of surgical treatment of ovarian cancer. Surgical treatment of ovarian cancer should therefore be confined to centers with the required infrastructure and expertise.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References and Recommended Reading

  1. 1.
    Krebs in Deutschland. Häufigkeiten und Trends. 2. Aktualisierte Ausgabe. Arbeitsgemeinschaft Bevölkerungsbezogener Krebsregister in Deutschland. 1999. http://www.rki.de/GBE/KREBS/KREBS.HTM. Accessed November 2, 2002.Google Scholar
  2. 2.
    Trends in SEER Incidence and U.S. Mortality, 1993–1997. Ovary Cancer (invasive). 2001. http:// www-seer.ims.nci.nih.gov/Publications/CSR7393/ovary.pdf. Accessed November 2, 2002.Google Scholar
  3. 3.
    Lichtenstein P, Holm NV, Verkasalo PK, et al.: Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000, 343:78–85.PubMedCrossRefGoogle Scholar
  4. 4.
    Averette HE, Hoskins W, Nguyen HN, et al.: National survey of ovarian carcinoma: I. A patient care evaluation study of the American College of Surgeons. Cancer 1993, 71:1629–1638.PubMedGoogle Scholar
  5. 5.
    Schutter EM, Kenemans P, Sohn C, et al.: Diagnostic value of pelvic examination, ultrasound, and CA 125 in postmenopausal women with a pelvic mass: an international multicenter study. Cancer 1994, 74:1389–1406.CrossRefGoogle Scholar
  6. 6.
    Le T, Krepart GV, Lotocki RJ, Heywood MS: Does debulking surgery improve survival in biologically aggressive ovarian carcinoma? Gynecol Oncol 1997, 67:208–214.PubMedCrossRefGoogle Scholar
  7. 7.
    Hightower RD, Nguyen HN, Averette HE, et al.: National survey of ovarian carcinoma. IV: Patterns of care and related survival for older patients. Cancer 1994, 73:377–383.PubMedCrossRefGoogle Scholar
  8. 8.
    Goodwin JS, Hunt WC, Samet JM: Determinants of cancer therapy in elderly patients. Cancer 1993, 72:594–601.PubMedCrossRefGoogle Scholar
  9. 9.
    Yancik R: Ovarian cancer: age contrasts in incidence, histology, disease stage at diagnosis, and mortality. Cancer 1993, 71(2 Suppl):517–523.PubMedCrossRefGoogle Scholar
  10. 10.
    Ries LA: Ovarian cancer: survival and treatment differences by age. Cancer 1993, 71(2 Suppl):524–529.PubMedCrossRefGoogle Scholar
  11. 11.
    Burger CW, Prinssen HM, Baak JPA, et al.: The management of borderline epithelial tumors of the ovary. Int J Gynecol Cancer 2000, 10:181–197. This is a good review about low malignancy potential tumor diagnosis, therapy, and prognosis.PubMedCrossRefGoogle Scholar
  12. 12.
    Kuhn W, Rutke S, Späthe K, et al.: Neoadjuvant chemotherapy followed by tumor debulking prolongs survival for patients with poor prognosis in International Federation of Gynecology and Obstetrics Stage IIIc ovarian carcinoma. Cancer 2001, 92:2585–25891. This paper shows the importance of achieving good surgical tumor resection even in advanced stages of ovarian cancer through cytotoxic tumor reduction.PubMedCrossRefGoogle Scholar
  13. 13.
    Bristow RE, Lagasse LD, Karlan BY: Secondary surgical cytoreduction for advanced epithelial ovarian cancer. Cancer 1996, 78:2049–2062.PubMedCrossRefGoogle Scholar

Copyright information

© Current Science Inc. 2003

Authors and Affiliations

  • Martin G. A. Bäuerle
    • 1
  • Rolf Kreienberg
    • 1
  • Tanja Volm
    • 1
  1. 1.Department of Gynecology and ObstetricsUniversity Hospital UlmUlmGermany

Personalised recommendations