Neurological Complications of Acute and Chronic Sinusitis

  • Andrea ZieglerEmail author
  • Monica Patadia
  • James Stankiewicz
Neurology of Systemic Diseases (J Biller, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Neurology of Systemic Disease


Purpose of Review

Acute and chronic sinusitis can give rise to a wide array of intracranial and orbital complications. These complications include brain abscess, subdural empyema, epidural abscess, meningitis, venous sinus thrombosis, frontal bone osteomyelitis, and orbital cellulitis and abscess. Despite numerous medical advances, these complications carry a risk of mortality and significant morbidity.

Recent Findings

Recent studies have shown improvement in both the mortality and the morbidity associated with the neurologic complications of acute and chronic sinusitis. However, there are still a large portion of patients with long-term sequelae, and the literature reports a morbidity rate of approximately 30%. The most common post-treatment morbidities include permanent changes in vision, seizures, and hemiparesis.


Although the overall incidence of neurologic complications from a sinogenic source are rare, the potential long-term complications can be devastating making prompt diagnosis and treatment vital to improving outcomes.


Neurologic complications Sinusitis Intracranial complications Orbital complications 


Compliance with Ethical Standards

Conflict of Interest

Andrea Ziegler, Monica Patadia, and James Stankiewicz declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Andrea Ziegler
    • 1
    • 2
    Email author
  • Monica Patadia
    • 1
  • James Stankiewicz
    • 1
  1. 1.Loyola University Medical CenterMaywoodUSA
  2. 2.Department of OtolaryngologyMaywoodUSA

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