Neurologic Complications in Treated HIV-1 Infection

  • Nisha S. BhatiaEmail author
  • Felicia C. Chow
Infection (J Halperin, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Infection


Effective combination antiretroviral therapy has transformed HIV infection into a chronic disease, with HIV-infected individuals living longer and reaching older age. Neurological disease remains common in treated HIV, however, due in part to ongoing inflammation and immune activation that persist in chronic infection. In this review, we highlight recent developments in our understanding of several clinically relevant neurologic complications that can occur in HIV infection despite treatment, including HIV-associated neurocognitive disorders, symptomatic CSF escape, cerebrovascular disease, and peripheral neuropathy.


Neurological complications HIV infection Viral suppression 


Compliance with Ethical Standards

Conflict of Interest

Nisha S. Bhatia and Felicia C. Chow declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of NeurologyUniversity of CaliforniaSan FranciscoUSA
  2. 2.Departments of Neurology and Medicine (Infectious Diseases)University of CaliforniaSan FranciscoUSA

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