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Neurologic Complications of Diabetes

  • Neurology of Systemic Disease (J Biller, Section Editor)
  • Published:
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Abstract

Neuropathy as a complication of diabetes is common and presents in a wide variety of clinical scenarios. Often the work-up is one of exclusion tempered with monitoring the response of symptoms to treatment options. The collaboration of a neurologist is often crucial to determining the best course of action for the patient. This review will address proposed pathogenic mechanisms and potential therapeutic interventions, both pharmacologic and nonpharmacologic.

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Abbreviations

IGF:

Insulin-like growth factors

NADPH:

Nicotinamide adenine dinucleotide phosphate hydrogen

NIS:

Neuropathy Impairment Score

RAGE:

Receptor for Advanced Glycation end products

TRP:

Transient receptor potential channel

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Gerald A. Charnogursky, Nicholas V. Emanuele, and Mary Ann Emanuele declare that they have no conflict of interest.

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    Gerald A. Charnogursky, Nicholas V. Emanuele & Mary Ann Emanuele

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Charnogursky, G.A., Emanuele, N.V. & Emanuele, M.A. Neurologic Complications of Diabetes. Curr Neurol Neurosci Rep 14, 457 (2014). https://doi.org/10.1007/s11910-014-0457-5

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