The Use of Targeted Temperature Management for Elevated Intracranial Pressure

Critical Care (SA Mayer, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Critical Care


The use of hypothermia for treatment of intracranial hypertension is controversial, despite no other medical therapy demonstrating consistent improvements in morbidity or mortality. Much of this may be the result of negative results from randomized controlled trials. However, the patients selected for these trials may have obscured the results in the populations most likely to benefit. Further, brain injury does not behave uniformly, not even within a diagnosis. Therefore, therapies may have more benefit in some diseases, less in others. This review focuses on the effect on outcome of intracranial hypertension in common disease processes in the neurocritical care unit, and identifies who is most likely to benefit from the use of hypothermia.


Targeted temperature management Hypothermia Normothermia Intracranial hypertension Intracerebral pressure Brain injury 


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of NeurologyMarshfield ClinicMarshfieldUSA

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