The Effects of Mozart’s Music on Interictal Activity in Epileptic Patients: Systematic Review and Meta-analysis of the Literature

  • Samaneh Sadat Dastgheib
  • Parvaneh Layegh
  • Ramin Sadeghi
  • Mohsen Foroughipur
  • Ali Shoeibi
  • Ali Gorji
Epilepsy (C Bazil, Section Editor)
First Online:
Part of the following topical collections:
  1. Topical Collection on Epilepsy

Abstract

Mozart’s music has been shown to have promising effects on nervous system functions. In this study, the effects of Mozart’s work on epilepsy were reviewed. Articles were obtained from a variety of sources. The results of 12 studies were extracted. Three different meta-analyses were performed to examine (i) the percentage of patients who had changes in their interictal epileptic discharges (IEDs) by music therapy; and the changes of IEDs (ii) during and (iii) after exposure to Mozart’s music. Data analysis indicated that 84 % of patients listening to Mozart’s music showed a significant decrease in IEDs. In addition, IEDs were decreased during (31.24 %) and after (23.74 %) listening to Mozart’s compositions. A noteworthy response to music therapy in patients with a higher intelligence quotient, generalized or central discharges, and idiopathic epilepsy was demonstrated. The effect of Mozart’s music on epilepsy seems to be significant. However, more randomized control studies are needed to determine its clinical efficacy.

Keywords

Intractable epilepsy Adjuvant therapy Music therapy Seizure attacks EEG 
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Notes

Compliance with Ethics Guidelines

Conflict of Interest

Samaneh Sadat Dastgheib, Parvaneh Layegh, Ramin Sadeghi, Mohsen Foroughipur, Ali Shoeibi, and Ali Gorji declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Samaneh Sadat Dastgheib
    • 1
  • Parvaneh Layegh
    • 2
    • 3
  • Ramin Sadeghi
    • 3
  • Mohsen Foroughipur
    • 4
  • Ali Shoeibi
    • 3
    • 4
    • 5
  • Ali Gorji
    • 1
    • 6
    • 7
    • 8
  1. 1.Shefa Neuroscience Research CenterTehranIran
  2. 2.Department of RadiologyMashhad University of Medical SciencesMashhadIran
  3. 3.Nuclear Medicine Research CenterMashhad University of Medical SciencesMashhadIran
  4. 4.Department of NeurologyMashhad University of Medical SciencesMashhadIran
  5. 5.Neurology DepartmentGhaem HospitalMashhadIran
  6. 6.Institut für Physiologie IWestfälische Wilhelms-Universität MünsterMünsterGermany
  7. 7.Klinik und Poliklinik für NeurochirurgieWestfälische Wilhelms-Universität MünsterMünsterGermany
  8. 8.Department of NeurologyWestfälische Wilhelms-Universität MünsterMünsterGermany

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