Neurogenic Stuttering: Its Reticular Modulation
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Abstract
Emerging neurologic evidence has suggested that developmental and acquired stuttering may have a cerebral base. Investigations have revealed compensatory activation in the right cortical motor areas and deactivation in the left perisylvian region in subjects with persistent developmental stuttering. The evidence has also implicated limbic (cingulate)-basal ganglia regions. Increased speech fluency with treatment in such subjects eliminated compensatory brain activity and shifted activation back to the left hemisphere. We assess the neurology of stuttering and then present our own observations of deep brain stimulation of the thalamus with some ameliorating effect on the encompassing syndrome with speech dysfluency.
Keywords
Acquired speech dysfluency Basal ganglia Centromedianum Facial dyskinesia Thalamocortical system Mesothalamic-reticular system Persistent developmental stutteringNotes
Acknowledgment
We thank Linda Helen, Elizabeth Kelley, and Bridget Zmotek for their assistance.
Disclosure
No potential conflicts of interest relevant to this article were reported.
References
Papers of particular interest, published recently, have been highlighted as: • Of importance
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