Current pharmacologic testing for horner syndrome
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- Mughal, M. & Longmuir, R. Curr Neurol Neurosci Rep (2009) 9: 384. doi:10.1007/s11910-009-0056-z
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First described in 1727, Horner syndrome occurs from injury to one of the three neurons in the oculo-sympathetic pathway. Its presence can be confirmed with pharmacologic testing, traditionally including cocaine testing with hydroxyamphetamine localization. More recently, apraclonidine testing has become a viable alternative in some practices. Concern has been raised regarding the possibility of false-negative results with apraclonidine testing as well as the safety of its use in young children.