Advertisement

Current Neurology and Neuroscience Reports

, Volume 4, Issue 2, pp 98–104 | Cite as

The epidemiology and impact of migraine

  • Marcelo E. Bigal
  • Richard B. Lipton
  • Walter F. Stewart
Article

Abstract

Migraine is a highly prevalent headache disorder that has a substantial impact on the individual and society. In this article, we review the burden of migraine, emphasizing the population-based studies that used standardized diagnostic criteria. We highlight descriptive epidemiology, burden of disease, patterns of diagnosis, and treatment. We focus on the epidemiology and burden of probable migraine, a subtype of migraine where just one clinical feature is missing. We finish by describing approaches to improving healthcare delivery for migraine and probable migraine. Although migraine is a remarkably common cause of temporary disability, many migraineurs, even those with disabling headache, have never consulted a physician for the problem. Prevalence is highest in women, in persons between the ages of 25 and 55 years, and, at least in the United States, in individuals from low-income households. Nonetheless, prevalence is high in groups other than these high-risk groups. Probable migraine is a prevalent form of migraine, and like migraine with and without aura it produces decrements in health-related quality of life and increments in disability relative to control subjects.

Keywords

Migraine Sumatriptan Migraine With Aura Headache Disorder Rizatriptan 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References and Recommended Reading

  1. 1.
    Linet MS, Celentano DD, Stewart WF: Headache characteristics associated with physician consultation: a population-based survey. Am J Prev Med 1991, 7:40–46.PubMedGoogle Scholar
  2. 2.
    Pascual J, Combarros O, Leno C, et al.: Distribution of headache by diagnosis as the reason for neurologic consultation. Med Clin 1995, 104:161–164.Google Scholar
  3. 3.
    Scher AI, Stewart WF, Lipton RB: Migraine and headache: a meta-analytic approach. In Epidemiology of Pain. Edited by Crombie IK. Seattle, WA: IASP Press; 1999:159–170.Google Scholar
  4. 4.
    Rasmussen BK: Epidemiology of headache. Cephalalgia 1995, 15:45–68.PubMedGoogle Scholar
  5. 5.
    Lipton RB, Amatniek JC, Ferrari MD, et al.: Migraine: identifying and removing barriers to care. Neurology 1994, 44(supp l6):56–62.Google Scholar
  6. 6.
    Headache classification committee of the International Headache Society: The International Classification of Headache Disorders. Cephalalgia 2004, 24(suppl 1);1–160.Google Scholar
  7. 7.
    Lipton RB, Stewart WF, Simon D: Medical consultation for migraine: results from the American Migraine Study. Headache 1998, 38:91–96.CrossRefGoogle Scholar
  8. 8.
    Lipton RB, Diamond S, Reed M, et al.: Migraine diagnosis and treatment: results from the American Migraine Study II. Headache 2001, 41:638–645. Important study.PubMedCrossRefGoogle Scholar
  9. 9.
    Lipton RB, Stewart WF, Diamond S, et al.: Prevalence and burden of migraine in the United States: data from the American Migraine Study II. Headache 2001, 41:646–657. Important study.PubMedCrossRefGoogle Scholar
  10. 10.
    Waters WE: Headache (Series in Clinical Epidemiology). Littleton, MA: PSG Co; 1986.Google Scholar
  11. 11.
    Headache classification committee of the International Headache Society: Classification and diagnostic criteria for headache disorders, cranial neuralgias, and facial pain. Cephalalgia 1988, 8(suppl 7):1–96.Google Scholar
  12. 12.
    Stewart WF, Linet MS, Celentano DD, et al.: Age and sex-specific incidence rates of migraine with and without visual aura. Am J Epidemiol 1993, 34:1111–1120.Google Scholar
  13. 13.
    Breslau N, Davis GC, Schultz LR, Peterson EL: Joint 1994 Wolff Award Presentation. Migraine and major depression: a longitudinal study. Headache 1994, 34:387–393.PubMedCrossRefGoogle Scholar
  14. 14.
    Stang PE, Yanagihara T, Swanson JW, et al.: Incidence of migraine headaches: a population-based study in Olmsted County, Minnesota. Neurology 1992, 42:1657–1662.PubMedGoogle Scholar
  15. 15.
    Lipton RB, Stewart WF, Celentano DD, Reed ML: Undiagnosed migraine: a comparison of symptom-based and self-reported physician diagnosis. Arch Intern Med 1992, 152:1273–1278.PubMedCrossRefGoogle Scholar
  16. 16.
    Lyngberg A, Jensen R, Rasmussen BK, Jorgensen T: Incidence of migraine in a Danish population-based follow-up study [abstract]. Cephalalgia 2003, 23:596.Google Scholar
  17. 17.
    Stewart WF, Simon D, Shechter A, Lipton RB: Population variation in migraine prevalence: a meta-analysis. J Clin Epidemiol 1995, 48:269–280.PubMedCrossRefGoogle Scholar
  18. 18.
    Henry P, Michel P, Brochet B, et al.: A nationwide survey of migraine in France: prevalence and clinical features in adults. Cephalalgia 1992, 12:229–237.PubMedCrossRefGoogle Scholar
  19. 19.
    Launer LJ, Terwindt GM, Ferrari MD: The prevalence and characteristics of migraine in a population-based cohort: the GEM Study. Neurology 1999, 53:537–542.PubMedGoogle Scholar
  20. 20.
    Steiner T, Scher A, Stewart W, et al.: The prevalence and disability burden of adult migraine in England and their relationships to age, gender and ethnicity. Cephalalgia 2003, 23:519–527.PubMedCrossRefGoogle Scholar
  21. 21.
    Sillanpaa M: Prevalence of migraine and other headache in Finnish children starting school. Headache 1976, 15:288–290.PubMedCrossRefGoogle Scholar
  22. 22.
    Amayo EO, Jowi JO, Njeru EK: Headache associated disability in medical students at the Kenyatta National Hospital, Nairobi. East Afr Med J 2002, 79:519–523.PubMedGoogle Scholar
  23. 23.
    Orji GI, Iloeje SO: Childhood migraine in Nigeria—I: a community-based study. West Afr J Med 1997, 16:208–217.PubMedGoogle Scholar
  24. 24.
    Matuja WB, Mteza IB, Rwiza HT: Headache in a nonclinical population in Dar es Salaam, Tanzania. A community-based study. Headache 1995, 35:273–276.PubMedCrossRefGoogle Scholar
  25. 25.
    Bille B: Migraine in school children. Acta Paediatr Scand 1962, 51(suppl 136):1–151.Google Scholar
  26. 26.
    Bille B: Migraine in children: prevalence, clinical features, and a 30-year follow-up. In Migraine and Other Headaches. Edited by Ferrari MD, Lataste X. New Jersey: Parthenon; 1989.Google Scholar
  27. 27.
    Sillanpaa M: Prevalence of migraine and other headache in Finnish children starting school. Headache 1976, 15:288–290.PubMedCrossRefGoogle Scholar
  28. 28.
    Sillanpaa M: Prevalence of headache in prepuberty. Headache 1983, 23:10–14.PubMedCrossRefGoogle Scholar
  29. 29.
    Silberstein SD, Merriam GR: Sex hormones and headache. In Blue Books of Practical Neurology: Headache. Edited by Goadsby P, Silberstein SD. Boston: Butterworth Heinemann; 1997:143–176.Google Scholar
  30. 30.
    Waters WE: Migraine: intelligence, social class, and familial prevalence. BMJ 1971, 2:77–81.PubMedGoogle Scholar
  31. 31.
    Stang PE, Sternfeld B, Sidney S: Migraine headache in a prepaid health plan: ascertainment, demographics, physiological and behavioral factors. Headache 1996, 36:69–76.PubMedCrossRefGoogle Scholar
  32. 32.
    Stang PE, Osterhaus JT: Impact of migraine in the United States: data from the National Health Interview Survey. Headache 1993, 33:29–35.PubMedCrossRefGoogle Scholar
  33. 33.
    Feinstein AR: The pretherapeutic classification of comorbidity in chronic disease. J Chronic Dis 1970, 23:455–468.CrossRefGoogle Scholar
  34. 34.
    Lipton RB, Silberstein SD: Why study the comorbidity of migraine. Neurology 1994, 44:4–5.Google Scholar
  35. 35.
    Hu XH, Markson LE, Lipton RB, et al.: Burden of migraine in the United States: disability and economic costs. Arch Intern Med 1999, 159:813–818.PubMedCrossRefGoogle Scholar
  36. 36.
    Lipton RB, Bigal ME, Kolodner K, et al.: The family impact of migraine: population-based studies in the USA and UK. Cephalalgia 2003, 23:429–440.PubMedCrossRefGoogle Scholar
  37. 37.
    Osterhaus JT, Gutterman DL, Plachetka JR: Health care resources and lost labor costs of migraine headaches in the United States. Pharmacoeconomics 1992, 2:67–76.PubMedGoogle Scholar
  38. 38.
    Holmes WF, MacGregor A, Dodick D: Migraine-related disability: impact and implications for sufferers’ lives and clinical issues. Neurology 2001, 56(suppl 1):S13-S19.PubMedGoogle Scholar
  39. 39.
    Celentano DD, Stewart WF, Lipton RB, Reed ML: Medication use and disability among migraineurs: a national probability sample. Headache 1992, 32:223–228.PubMedCrossRefGoogle Scholar
  40. 40.
    Fry J: Profiles of Disease. Edinburgh: Livingstone; 1996.Google Scholar
  41. 41.
    Consumer Healthcare Products Association: OTC Sales Statistics: 1995–1999. New York: AC Neilsen; April, 2000.Google Scholar
  42. 42.
    Rains JC, Penzien DB, Lipchik GL, et al.: Diagnosis of migraine: empirical analysis of a large clinical sample of atypical migraine (IHS 1.7) patients and proposed revision of the IHS criteria. Cephalalgia 2001, 21:584–595.PubMedCrossRefGoogle Scholar
  43. 43.
    Russell MB, Olesen J: Migrainous disorder and its relation to migraine without aura and migraine with aura. A genetic epidemiological study. Cephalalgia 1996, 16:431–435.PubMedCrossRefGoogle Scholar
  44. 44.
    Lipton RB, Stewart WF, von Korff M: Burden of migraine: societal costs and therapeutic opportunities. Neurology 1997, 48(suppl 3):4–9.Google Scholar
  45. 45.
    Cady RC, Ryan R, Jhingran P, et al.: Sumatriptan injection reduces productivity loss during a migraine attack: results of a double-blind, placebo-controlled trial. Arch Intern Med 1998, 158:1013–1018.PubMedCrossRefGoogle Scholar
  46. 46.
    Dahlof C, Bouchard J, Cortelli P, et al.: A multinational investigation of the impact of subcutaneous sumatriptan. II: Health-related quality of life. Pharmacoeconomics 1997, 11(suppl 1):24–34.PubMedCrossRefGoogle Scholar
  47. 47.
    Santanello NC, Polis AB, Hartmaier SL, et al.: Improvement in migraine-specific quality of life in a clinical trial of rizatriptan. Cephalalgia 1997, 17:867–872.PubMedCrossRefGoogle Scholar
  48. 48.
    Lipton RB, Dodick D, Sadovsky R, et al.: A self-administered screener for migraine in primary care: the ID Migraine(TM) validation study. Neurology 2003, 61:375–382.PubMedGoogle Scholar
  49. 49.
    Matchar DB, Young WB, Rosenerg J, et al.: Multispecialty consensus on diagnosis and treatment of headache: pharmacological management of acute attacks. Neurology 2000, 54. http://www.aan.com/public/practiceguidelines/03.pdf.Google Scholar

Copyright information

© Current Science Inc 2004

Authors and Affiliations

  • Marcelo E. Bigal
    • 1
  • Richard B. Lipton
  • Walter F. Stewart
  1. 1.Department of NeurologyAlbert Einstein College of MedicineBronxUSA

Personalised recommendations