The Role of PCR in the Diagnosis of Candida Vulvovaginitis—a New Gold Standard?

Genitourinary Infections (J Sobel, Section Editor)

DOI: 10.1007/s11908-015-0488-3

Cite this article as:
Sobel, J.D. & Akins, R.A. Curr Infect Dis Rep (2015) 17: 33. doi:10.1007/s11908-015-0488-3
Part of the following topical collections:
  1. Topical Collection on Genitourinary Infections


PCR is recognized as a reliable technique for detection of all types of microorganisms. Being highly objective and reproducible also sensitive and specific, PCR is now widely used for sexually transmitted infection (STI) diagnosis. Potential, however, exists for detecting non-pathogens, and not identifying a pathogenic state decreases specificity or clinical significance. PCR Candida tests of vaginal specimens are now widely available and frequently used offering a modest to moderate increase in sensitivity and are likely to replace traditional culture and DNA homology testing. Nevertheless, there remain considerable gaps in our knowledge regarding the usefulness and applications of these expensive tests.


Diagnosis Candida Vulvovaginitis PCR Vulvovaginal 

Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Division of Infectious Diseases, Department of Internal MedicineWayne State University School of MedicineDetroitUSA
  2. 2.Department of Biochemistry & Molecular BiologyWayne State University School of MedicineDetroitUSA

Personalised recommendations