Current Infectious Disease Reports

, Volume 15, Issue 3, pp 236–241

Long-Term Sequelae of Childhood Bacterial Meningitis

  • Lee D. Hudson
  • Russell M. Viner
  • Deborah Christie
PEDIATRIC INFECTIOUS DISEASES (I BROOK, SECTION EDITOR)

DOI: 10.1007/s11908-013-0332-6

Cite this article as:
Hudson, L.D., Viner, R.M. & Christie, D. Curr Infect Dis Rep (2013) 15: 236. doi:10.1007/s11908-013-0332-6

Abstract

In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial meningitis. Outcomes vary by bacterial pathogen, with around a 20 % risk for severe sequelae (most commonly, neurocognitive) by all pathogenic causes. Pneumococcal, tuberculosis, and group B streptococcal meningitis lead to the highest rates of sequelae. Recent epidemiological shifts in the major pathogens causing meningitis, as well as varied regional settings between studies, limit generalizability of evidence in the literature, and better research using longitudinal data and case–control methodology is required, especially in low-income countries. However, the consistently high levels of complications described in the literature call for more widespread vaccination programs for prevention and a greater focus on potential complications by educators and health-care providers to support childhood survivors of bacterial meningitis and their families.

Keywords

Children Bacterial Meningitis Complications Outcomes 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Lee D. Hudson
    • 1
    • 2
  • Russell M. Viner
    • 1
    • 2
  • Deborah Christie
    • 1
    • 2
  1. 1.University College London HospitalLondonUK
  2. 2.General and Adolescent Paediatric UnitUCL Institute of Child HealthLondonUK

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