Current Infectious Disease Reports

, Volume 14, Issue 6, pp 668–675 | Cite as

Emerging Invasive Fungal Diseases in Transplantation

  • Perrine Parize
  • Blandine Rammaert
  • Olivier Lortholary
Transplant and Oncology (MG Ison, Section Editor)

Abstract

Invasive fungal infections continue to be a major cause of morbidity and mortality in severely immunocompromised transplant patients. Although Candida spp. and Aspergillus spp. represent the majority of identified pathogens, other fungi have become increasingly prevalent among this patient population. Diagnosis and treatment of invasive fungal infections remain a challenge in transplant medicine despite recent major advances. In this review, we will emphasize emerging topics in invasive fungal infections in transplantations that occurred in 2011–2012. The current literature was reviewed to synthesize new trends in epidemiology, recent outbreaks, clinical findings, and advances in diagnostic and therapeutic resources.

Keywords

Solid organ transplantation Hematopoietic stem cell transplantation Mucormycosis Health-care-associated infection Pneumocystis pneumonia 

Notes

Disclosure

P. Parize has received grant support from patient association “Vaincre la mucoviscidose” and travel and accommodation support from Sanofi; B. Rammaert has received honoraria from Gilead and travel and accommodation support from MSD; O. Lortholary is a member of the MSD board, is a consultant for Astellas and Gilead Sciences and received grants speaker's fees from MSD, Astellas, Gilead Sciences and Pfizer.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Perrine Parize
    • 1
  • Blandine Rammaert
    • 1
  • Olivier Lortholary
    • 1
    • 2
  1. 1.Université Paris-Descartes, Sorbonne Paris Cité, Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, APHP, Centre d’Infectiologie Necker-Pasteur, Institut Hospitalo-Universitaire ImagineParis Cedex 15France
  2. 2.Institut Pasteur, Centre National de Référence Mycoses Invasives et Antifongiques, CNRS URA3012ParisFrance

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