Emerging Invasive Fungal Diseases in Transplantation
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Invasive fungal infections continue to be a major cause of morbidity and mortality in severely immunocompromised transplant patients. Although Candida spp. and Aspergillus spp. represent the majority of identified pathogens, other fungi have become increasingly prevalent among this patient population. Diagnosis and treatment of invasive fungal infections remain a challenge in transplant medicine despite recent major advances. In this review, we will emphasize emerging topics in invasive fungal infections in transplantations that occurred in 2011–2012. The current literature was reviewed to synthesize new trends in epidemiology, recent outbreaks, clinical findings, and advances in diagnostic and therapeutic resources.
KeywordsSolid organ transplantation Hematopoietic stem cell transplantation Mucormycosis Health-care-associated infection Pneumocystis pneumonia
P. Parize has received grant support from patient association “Vaincre la mucoviscidose” and travel and accommodation support from Sanofi; B. Rammaert has received honoraria from Gilead and travel and accommodation support from MSD; O. Lortholary is a member of the MSD board, is a consultant for Astellas and Gilead Sciences and received grants speaker's fees from MSD, Astellas, Gilead Sciences and Pfizer.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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