Type-specific serologic testing for herpes simplex virus-2
- 34 Downloads
Genital herpes due to infection with herpes simplex virus-2 (HSV-2) affects an estimated 60 million adults in the United States. Over 90% are unaware of their infection but are at risk of transmitting HSV to partners. This ongoing “silent” disease is responsible for the continued increase in HSV prevalence. The recent advent of type-specific serologic tests has allowed accurate differentiation of HSV-1 and HSV-2 infection. Screening of at-risk populations will allow identification of individuals with genital herpes and provide an opportunity for risk reduction counseling and interventions to reduce transmission.
Unable to display preview. Download preview PDF.
References and Recommended Reading
- 9.Fleming DT, Wasserheit JN: From Epidemiologic synergy to public health policy and practice: the contribution of other sexually transmitted diseases to transmission of HIV infection. Sex Transm Infect 1999, 75:3–17. Excellent overview of the epidemiologic data supporting contribution of STDs to HIV acquisition and transmission. This article coined the term epidemiologic synergy describing the population-based relationship of STDs with HIV.PubMedCrossRefGoogle Scholar
- 17.Clinical Effectiveness Group: National guideline for the management of genital herpes. Sex Transm Infect 1999, 75(Suppl 1):S24-S28.Google Scholar
- 23.Koutsky LA, Ashley RL, Holmes KK, et al.: The frequency of unrecognized type 2 herpes simplex virus infection among women: implications for the control of genital herpes. Sex Transm Dis 1990, 12:90–94.Google Scholar
- 26.Corey L: Valacyclovir prevents transmission of sexually transmitted genital herpes. Paper presented at the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Diego. September 27–30, 2002.Google Scholar
- 30.Wald A, Baseman J, Selke S, et al.: Sexual transmission of genital herpes simplex virus (HSV): a time to event analysis of risk factors associated with rapid acquisition [abstract 6]. In Program and Abstracts of the 2000 National STD Prevention Conference (Milwaukee). Washington, DC: Department of Health and Human Services; 2000.Google Scholar
- 32.ACOG Committee on Practice Bulletins: Clinical management guidelines for obstetricians-gynecologists. ACOG Pract Bull 1999, 8:1–9.Google Scholar