Current Hypertension Reports

, 16:488

Invasive Treatment of Resistant Hypertension: Present and Future

Resistant Hypertension (E Pimenta, Section Editor)

DOI: 10.1007/s11906-014-0488-y

Cite this article as:
Ott, C. & Schmieder, R.E. Curr Hypertens Rep (2014) 16: 488. doi:10.1007/s11906-014-0488-y
Part of the following topical collections:
  1. Topical Collection on Resistant Hypertension


The underlying pathophysiologic concept of diverse invasive devices to treat resistant hypertension (e.g., sympathetic denervation, carotid sinus nerve stimulation) is known for a long time. Since the pioneering work in the 1940s in humans, innovative techniques have been developed resulting in less invasive treatment procedures and, hence, overcoming serious side effects, which in turn improved safety and lead to more widespread use. Recently, new experimental technologies have been or are under evaluation in experiments and first-in-man studies have been conducted. Data with interventional techniques are rapidly expanding and have to be interpreted with caution. Additional data from randomized potentially sham-controlled studies are urgently needed. This article focuses on the increasing work of different invasive approaches for the treatment of resistant hypertension.


Arteriovenous anastomosis Carotid baroreceptor stimulation Carotid body ablation Catheter Ethanol Intervention Guidelines Neurovascular compression Renal artery stenosis Renal denervation Treatment resistant hypertension Ultrasound 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Nephrology and HypertensionUniversity Hospital of the Friedrich-Alexander-University Erlangen-NürnbergErlangenGermany

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