Sleep Disturbances and Resistant Hypertension: Association or Causality?
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Two main sleep disturbances, namely obstructive sleep apnea (OSA) and sleep deprivation, have gained growing interest in the field of hypertension research. This fact is supported not only by evidence that both disturbances are quite common in modern societies but also that OSA and sleep deprivation are associated with several pathways that may contribute to a predisposition to hypertension or even exacerbate blood pressure levels in hypertensive patients. In the present review, we will discuss current evidence supporting a potential role of these sleep disturbances in the resistant hypertension scenario.
KeywordsCardiovascular risk Hypertension Sleep apnea Sleep deprivation Sleep disturbances
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Conflict of Interest Daniel Castanho Genta-Pereira, Rodrigo P. Pedrosa, Geraldo Lorenzi-Filho, and Luciano F. Drager declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent This article does not contain any studies with human or animal subjects performed by any of the authors.
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