Hypertension as a Risk Factor for Heart Failure

Hypertension and the Heart (SD Solomon and O Vardeny, Section Editors)

DOI: 10.1007/s11906-014-0447-7

Cite this article as:
Kannan, A. & Janardhanan, R. Curr Hypertens Rep (2014) 16: 447. doi:10.1007/s11906-014-0447-7
Part of the following topical collections:
  1. Topical Collection on Hypertension and the Heart


Hypertension remains a significant risk factor for development of congestive heart failure CHF), with various mechanisms contributing to both systolic and diastolic dysfunction. The pathogenesis of myocardial changes includes structural remodeling, left ventricular hypertrophy, and fibrosis. Activation of the sympathetic nervous system and renin-angiotensin system is a key contributing factor of hypertension, and thus interventions that antagonize these systems promote regression of hypertrophy and heart failure. Control of blood pressure is of paramount importance in improving the prognosis of patients with heart failure.


Congestive heart failure Hypertension Left ventricular hypertrophy 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Section of Cardiology, Sarver Heart CenterUniversity of Arizona College of MedicineTucsonUSA
  2. 2.Section of Inpatient MedicineTucsonUSA
  3. 3.Sarver Heart CenterUniversity of ArizonaTucsonUSA

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