Current Hypertension Reports

, Volume 12, Issue 6, pp 474–479 | Cite as

Nighttime Blood Pressure: A Target for Therapy?

  • Bernard Waeber
  • Jean-Jacques Mourad
  • Eoin O’Brien
Article

Abstract

Ambulatory blood pressure (BP) monitoring is increasingly used in the evaluation of hypertensive patients. The ability to monitor BP throughout the day and night allows the detection of abnormal nocturnal BP patterns, the most common being a “nondipping” pattern, which is associated with increased cardiovascular risk; its correction appears to have a positive impact on cardiovascular outcome. Antihypertensive treatment should be individually adjusted to control BP during both daytime and nighttime. However, drug-induced lowering of nocturnal BP, if excessive, could amplify the morning BP surge in patients with daytime BP elevation, increasing the risk of developing a cardiovascular event. Ambulatory BP monitoring therefore represents a unique tool to establish the most appropriate antihypertensive drug regimen for the individual patient.

Keywords

Ambulatory blood pressure Morning surge Nighttime blood pressure Cardiovascular risk Dipper pattern Nondipping pattern 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Bernard Waeber
    • 1
  • Jean-Jacques Mourad
    • 2
  • Eoin O’Brien
    • 3
  1. 1.Division of Clinical PathophysiologyCentre Hospitalier Universitaire VaudoisLausanneSwitzerland
  2. 2.Hôpital AvicenneBobignyFrance
  3. 3.The Conway Institute of Biomolecular and Biomedical ResearchDublin 4Ireland

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