The relationship between quality of life and adherence to treatment
- 160 Downloads
Hypertension is a preventable condition, and the outcomes of clinical trials have established that its treatment reduces cardiovascular morbidity and mortality. Although awareness about the disease has improved in the past two decades, the reality is that many people remain untreated or not adequately controlled. The treatment of hypertension is usually long term, and its success will depend on the effects of the drug regimen on the patient’s quality of life. The relationship between quality of life and compliance is complex and merits careful study. Monitoring quality of life may be one of the best ways of improving adherence to treatment. Therefore, when developing an approach to the treatment of hypertension, physicians should take into consideration the impact of different antihypertensives on the patient’s overall well being, and along with the side effects and contraindications, quality-of-life issues may determine the choice of medication.
KeywordsNifedipine Captopril Atenolol Bisoprolol Cilazapril
Unable to display preview. Download preview PDF.
References and Recommended Reading
- 4.Bulpitt CJ, Fletcher AE: Quality of life evaluation of antihypertensive drugs. Pharmacoeconomics 1992, 2:95–102.Google Scholar
- 7.Kittler ME: Elderly hypertensives and quality of life: some methodological considerations. Eur Heart J 1994, 14:113–121.Google Scholar
- 9.vanRossum CTM, van de Mheen H, Witteman JCM, et al.: Prevalence, treatment, and control of hypertension by sociodemographic factors among the Dutch elderly. Hypertension 2000, 35:814–821. A cross-sectional analysis of subjects in the Rotterdam Study revealed that 25% and 18% of hypertensive men and women, respectively, were not aware of having hypertension.PubMedGoogle Scholar
- 10.Server P: The heterogeneity of hypertension: why doesn’t every patient respond to every antihypertensive drug? J Hum Hypertens 1995, 9:S33-S36.Google Scholar
- 12.Testa MA: Methods and applications of quality-of-life measurement during antihypertensive therapy. Curr Hypertens Rep 2000, 2:530–537. According to the author of this study, the assessment of the pharmacologic effects of antihypertensive drugs on the patient’s wellness should focus on elements of health-related quality of life, which affect the patient’s compliance.PubMedGoogle Scholar
- 17.Bulpitt CJ, Fletcher AE: Quality of life evaluation of antihypertensive drugs. Pharmacoeconomics 1992, 2:95–102.Google Scholar
- 18.Bulpitt CJ, Connor M, Schulte M, Fletcher AE: Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life. J Hum Hypertens 2000, 14:205–212. s study compared the effects of the β-blocker bisoprolol versus the calcium channel blocker nifedipine on quality of life. The results of the study support the argument that β-blockers have an additional benefit in reducing tension and anxiety.PubMedCrossRefGoogle Scholar