HIV and Aging in Mainland China: Implications for Control and Prevention Research

  • Na HeEmail author
  • Yingying Ding
  • Jing Li
  • Shiying Yuan
  • Lulu Xu
  • Shijie Qiao
  • Xiaohui Xu
  • Bowen Zhu
  • Ruizi Shi
  • John P. Barile
  • Frank Y. WongEmail author
The Global Epidemic (SH Vermund, Section Editor)
Part of the following topical collections:
  1. Topical Collection on The Global Epidemic


Purpose of Review

The last 15 years have witnessed a dramatic change in HIV-related epidemiology amidst improvements in treatment and care in China. With proper treatment, HIV is now considered a chronic disease. As a consequence, many people living with HIV (PLWH) now present age-related comorbidities. We reviewed 13 topical issues concerning the epidemiology of aging with HIV in mainland China.


Many of aging-related issues associated with the biological and physical aspects of living with HIV addressed in mainland China are consistent with the global literature. Greater prevalence of age-related comorbidities among PLWH was observed. Beyond biological mechanisms associated with HIV infection and traditional risk factors, other factors play a vital role in the aging process among PLWH.


A stronger focus on screening, prevention, and management of non-HIV co-morbidities among PLWH is now warranted. Macro-social factors need to be integrated into next generation of clinical and/or behavioral HIV research to inform disease progression and management as well as prevention.


Aging HIV Age-related diseases Risk factors China 


Funding Information

This research was supported by grants from the National Natural Science Foundation of China (81773485, 81872671, 81803291) and the China National Science and Technology Major Projects on Infectious Diseases (2018ZX10721102-004) and partially supported by Shanghai Municipal Health and Family Planning Commission (GWTD2015S05).

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Na He
    • 1
    • 2
    Email author
  • Yingying Ding
    • 1
  • Jing Li
    • 1
  • Shiying Yuan
    • 1
  • Lulu Xu
    • 1
  • Shijie Qiao
    • 1
  • Xiaohui Xu
    • 1
  • Bowen Zhu
    • 1
  • Ruizi Shi
    • 1
  • John P. Barile
    • 3
  • Frank Y. Wong
    • 1
    • 3
    • 4
    Email author
  1. 1.Department of Epidemiology, School of Public Health, The Key Laboratory of Public Health Safety of Ministry of EducationFudan UniversityShanghaiChina
  2. 2.Key Laboratory of Health Technology Assessment of Ministry of HealthFudan UniversityShanghaiChina
  3. 3.Department of PsychologyUniversity of Hawai’i at MānoaHonoluluUSA
  4. 4.Center for Indigenous Nursing Research for Health EquityFlorida State UniversityTallahasseeUSA

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