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Current HIV/AIDS Reports

, Volume 15, Issue 5, pp 359–370 | Cite as

A Dissemination and Implementation Science Approach to the Epidemic of Opioid Use Disorder in the United States

  • Stephanie M. Mathis
  • Nicholas Hagemeier
  • Angela Hagaman
  • John Dreyzehner
  • Robert P. PackEmail author
The Global Epidemic (SH Vermund, Section Editor)
Part of the following topical collections:
  1. Topical Collection on The Global Epidemic

Abstract

Purpose of Review

This review aims to (1) conceptualize the complexity of the opioid use disorder epidemic using a conceptual model grounded in the disease continuum and corresponding levels of prevention and (2) summarize a select set of interventions for the prevention and treatment of opioid use disorder.

Recent Findings

Epidemiologic data indicate non-medical prescription and illicit opioid use have reached unprecedented levels, fueling an opioid use disorder epidemic in the USA. A problem of this magnitude is rooted in multiple supply- and demand-side drivers, the combined effect of which outweighs current prevention and treatment efforts. Multiple primary, secondary, and tertiary prevention interventions, both evidence-informed and evidence-based, are available to address each point along the disease continuum—non-use, initiation, dependence, addiction, and death.

Summary

If interventions grounded in the best available evidence are disseminated and implemented across the disease continuum in a coordinated and collaborative manner, public health systems could be increasingly effective in responding to the epidemic.

Keywords

Opioid use disorder Non-medical use Addiction Prevention Dissemination Implementation science 

Notes

Funding

The work was supported in part by the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH) under award R24DA036409. The content is solely the responsibility of the authors and does not necessarily represent the official views of NIH.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Stephanie M. Mathis
    • 1
    • 2
  • Nicholas Hagemeier
    • 2
    • 3
  • Angela Hagaman
    • 1
    • 2
  • John Dreyzehner
    • 4
  • Robert P. Pack
    • 1
    • 2
    Email author
  1. 1.College of Public HealthEast Tennessee State UniversityJohnson CityUSA
  2. 2.Center for Prescription Drug Abuse Prevention and TreatmentEast Tennessee State UniversityJohnson CityUSA
  3. 3.Bill Gatton College of PharmacyEast Tennessee State UniversityJohnson CityUSA
  4. 4.Tennessee Department of HealthNashvilleUSA

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