Current HIV/AIDS Reports

, Volume 10, Issue 3, pp 199–206 | Cite as

Cardiovascular Disease and HIV Infection

  • Virginia A. TriantEmail author
Metabolic Complications and Comorbidity (JM Kilby, Section Editor)


The emergence of chronic disease complications in controlled HIV disease has changed the landscape of HIV clinical care. HIV infection confers an increased cardiovascular disease risk, which is thought to be due to a complex interplay of mechanistic factors. While traditional cardiovascular risk factors likely play a role, recent evidence suggests that HIV-associated inflammation and immune activation are important mediators of cardiovascular risk. It is unclear whether established preventative interventions for the general population are applicable to HIV-infected patients, and the need to translate mechanistic knowledge into HIV-specific clinical interventions represents an important priority. Developing strategies to prevent cardiovascular disease in HIV-infected individuals calls for a multidisciplinary approach and represents an opportunity to exert a major public health impact in an at-risk population.


HIV Cardiovascular Coronary Myocardial infarction Risk factors 


Compliance with Ethics Guidelines

Conflict of Interest

Virginia A. Triant declares that she has no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Divisions of Infectious Diseases and General MedicineMassachusetts General Hospital and Harvard Medical SchoolBostonUSA

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