Predicting Future Complications of Cirrhosis

  • Joel WeddEmail author
  • Kavitha Nair
Management of Cirrhotic Patient (A Cardenas and P Tandon, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Management of the Cirrhotic Patient


Purpose of Review

Decompensated cirrhosis and liver failure result in high mortality risk. Identifying the severity of illness and risk of poor outcomes is important for improved clinical decision making. This review serves to examine the currently in practice and developing tools for prognosticating patients with cirrhosis.

Recent Findings

The Child–Turcotte–Pugh (CTP) score and Model for End-Stage Liver Disease (MELD) score are the most used prognostic tools for cirrhotic patients. More recently, however, are newly developing biochemical models and imaging tools that strive to improve upon the MELD score.


Significant effort has been dedicated to revising, complementing, or replacing the MELD score for prognostication and for transplant allocation. Ongoing adjustment to current prognostication methods and the search for new paradigms promises improved ability to predict outcomes and determine the best management in the future.


Cirrhosis Prognostic factors Chronic liver disease Liver transplant Model for end-stage liver disease (MELD) 


Compliance with Ethical Standards

Conflicts of Interest

Joel Wedd and Kavitha Nair each declare no potential conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Emory Transplant CenterEmory University School of MedicineAtlantaUSA

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