Prevention and Management of Hepatitis B in Healthcare Professionals

  • Corey R. O’Brien
  • Joseph K. LimEmail author
Hepatitis B (J Lim, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Hepatitis B


Purpose of Review

To review the epidemiology of hepatitis B virus (HBV) transmission in the healthcare setting and outline best practices in the prevention and management of chronic HBV in healthcare professionals.

Recent Findings

Hepatitis B virus (HBV) infection remains a global public health burden and chronically infects an estimated 257 million persons worldwide. HBV represents one of the most important occupational risks for healthcare workers (HCWs) due to efficient transmission through percutaneous exposure of HBV-infected blood and blood-contaminated body fluids. Although the incidence of HCW-patient transmission of HBV has decreased significantly since 2000, ongoing deficits in HCW testing, vaccination, and confirmation of immunity, as well as post-exposure management protocols, raise concern for ongoing risk for nosocomial exposure.


Established recommendations of the AASLD, CDC, and SHEA provide guidance to clinicians on the prevention and management of chronic HBV in healthcare professionals.


Hepatitis B Healthcare professionals Needlestick injury Occupational health Vaccination 


Compliance with Ethical Standards

Conflict of Interest

Joseph K. Lim reports grants from AbbVie, grants from Allergan, grants and personal fees from Bristol-Myers Squibb, grants from Conatus, grants from Genfit, grants from Gilead, grants from Intercept, outside the submitted work. Corey R. O’Brien declares no potential conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Internal MedicineYale University School of MedicineNew HavenUSA
  2. 2.Yale Liver Center and Section of Digestive DiseasesYale University School of MedicineNew HavenUSA

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