Current Hepatitis Reports

, Volume 6, Issue 2, pp 39–45 | Cite as

The impact of steatosis and alcohol on hepatitis C

  • Sam Galhenage
  • Manal F. AbdelmalekEmail author


Alcohol consumption and hepatic steatosis interact synergistically with hepatitis C virus (HCV) to accelerate fibrosis progression and reduce the efficacy of standard antiviral therapies. Research aimed at delineating the viral and host interactions involved in the pathogenesis of steatosis in HCV infection may provide novel therapeutic strategies that can modify disease progression and improve treatment response. This review discusses the clinical aspects of HCV fibrosis progression and treatment response in the setting of alcohol use or hepatic steatosis.


Chronic Hepatitis NASH Antiviral Therapy Hepatic Steatosis Nonalcoholic Fatty Liver Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Medicine Group, LLC 2007

Authors and Affiliations

  1. 1.Division of Gastroenterology, Hepatology & NutritionDuke University Medical CenterDurhamUSA

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