Current Hematologic Malignancy Reports

, Volume 9, Issue 4, pp 340–349 | Cite as

Epidemiology of MPN: What Do We Know?

Myeloproliferative Disorders (C Harrison, Section Editor)


The myeloproliferative neoplasms, are characterised by overproduction of myeloid cells. Chronic myeloid leukaemia, polycythaemia vera, essential thrombocythaemia, myelofibrosis and the very rare disorders chronic neutrophilic leukaemia, chronic eosinophilic leukaemia not otherwise specified and mastocytosis are all included in the group. Incidence and prevalence rates reported in the worldwide literature are presented in this review. Survival data on each condition is described. Information on the aetiology of the disorders is discussed including body mass index, diet, smoking and alcohol, allergies, associated medical conditions, occupation and environmental exposures with focus on recent new studies. The aetiology of the myeloproliferative neoplasms remains unknown, and this review of the current state of knowledge highlights the need for further comprehensive research.


Epidemiology Myeloproliferative neoplasms Survival Body mass index Diet Benzene 


Conflict of Interest

Dr. Lesley Anderson and Dr. Mary Frances McMullin each declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by either of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Centre for Public HealthQueen’s University BelfastBelfastNorthern Ireland
  2. 2.Centre for Cancer Research and Cell BiologyQueen’s University BelfastBelfastNorthern Ireland

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