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Current Heart Failure Reports

, Volume 6, Issue 4, pp 257–264 | Cite as

Tachycardia-mediated cardiomyopathy: Recognition and management

  • Rakesh Gopinathannair
  • Renee M. Sullivan
  • Brian OlshanskyEmail author
Article

Abstract

Tachycardia-mediated cardiomyopathy is a cause of ventricular dysfunction due to, at least partially, persistent tachycardia leading to cellular and extracellular perturbations. Cardiomyopathy may take years to develop, but pharmacologic management to achieve rate control and reverse remodeling, as well as cardioversion or ablative strategies to stop the tachycardia, can result in rapid recovery from symptoms and gradual improvement in left ventricular ejection fraction. However, ultrastructural changes can remain and may lead to a rapid decline in ventricular function if tachycardia recurs. Ultrastructural changes may also explain a propensity toward sudden death even if the ejection fraction normalizes. Although the etiology, pathophysiology, and late clinical manifestations of tachycardia-mediated cardiomyopathy are beginning to be understood, investigation continues, focusing on prevention, early recognition, and acute and long-term management in an attempt to lessen heart failure and prevent risk of sudden death.

Keywords

Cardiomyopathy Left Ventricular Ejection Fraction Amiodarone Catheter Ablation Atrial Tachycardia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Rakesh Gopinathannair
  • Renee M. Sullivan
  • Brian Olshansky
    • 1
    Email author
  1. 1.University of Iowa HospitalsIowa CityUSA

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