Current Heart Failure Reports

, Volume 6, Issue 4, pp 229–235

Modulation of left ventricular dilation remodeling with epicardial restraint devices in postmyocardial infarction heart failure

  • Veli K. Topkara
  • Srikanth Kondareddy
  • Douglas L. Mann


Myocardial infarction initiates progressive changes in the biology of the myocyte and nonmyocyte components of the myocardium, as well as the geometry of the left ventricle. Despite the use of evidence-based strategies to postmyocardial infarction, heart failure supervenes and is attended by an unacceptably high mortality rate. Given that left ventricular (LV) remodeling may contribute independently to disease progression, several innovative approaches have been designed to attenuate and reverse LV remodeling. This review discusses the emerging role of epicardial restraint devices in the treatment of postmyocardial cardiac remodeling.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Veli K. Topkara
  • Srikanth Kondareddy
  • Douglas L. Mann
    • 1
  1. 1.Cardiovascular DivisionWashington University School of MedicineSaint LouisUSA

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