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Imaging of Hepatic Fibrosis

  • Rishi Philip Mathew
  • Sudhakar Kundapur Venkatesh
Liver (E Kallwitz and S Cotler, Section Editors)
  • 296 Downloads
Part of the following topical collections:
  1. Topical Collection on Liver

Abstract

Purpose of Review

The purpose of this review is to discuss the current imaging techniques for non-invasive assessment of liver fibrosis (LF).

Recent Findings

Elastography-based techniques are the most widely used imaging methods for the evaluation of LF. Currently, MR elastography (MRE) is the most accurate non-invasive method for detection and staging of LF. Ultrasound-based vibration-controlled transient elastography (VCTE) is the most widely used as it can be easily performed at the point of care but has technical limitations especially in the obese. Innovations and technical improvements continue to evolve in elastography for improving accuracy and avoiding misinterpretation from confounding factors. Other imaging methods including diffusion-weighted imaging (DWI), hepatocellular contrast-enhanced (HCE) MRI, T1 relaxometry, T1ρ imaging, textural analysis, liver surface nodularity, susceptibility-weighted imaging, and perfusion imaging are promising but need further evaluation and clinical validation.

Summary

MRE is the most accurate imaging technique for assessment of LF.

Keywords

Liver fibrosis Functional imaging Magnetic resonance elastography 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Rishi Philip Mathew
    • 1
  • Sudhakar Kundapur Venkatesh
    • 1
  1. 1.Department of Radiology, Mayo ClinicMayo Clinic College of MedicineRochesterUSA

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