Current Gastroenterology Reports

, Volume 14, Issue 6, pp 489–496 | Cite as

Helicobacter pylori in Gastric Malignancies

  • Abhishek Bhandari
  • Sheila E. CroweEmail author
Stomach and Duodenum (J Pisegna, Section Editor)


Helicobacter pylori infection remains common worldwide and is significantly associated with gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT)lymphoma. This article reviews recent developments in the field of H. pylori with an emphasis on mechanisms of carcinogenesis, and the bacterial, environmental and host factors that may alter risk of developing gastric cancer or gastric MALT lymphoma. The topic of eradication of H. pylori to prevent the development of malignancy and the possibility of a vaccine against H. pylori are also explored.


Helicobacter Pylori Gastric Malignancy Adenocarcinoma MALT Lymphoma Cancer Stomach Mucosa-associated lymphoid tissue 



No potential conflicts of interest relevant to this article were reported.


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© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of MedicineUniversity of California, San DiegoLa JollaUSA
  2. 2.Division of Gastroenterology, Department of MedicineUniversity of California, San DiegoLa JollaUSA

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