Current Gastroenterology Reports

, Volume 13, Issue 3, pp 226–239

Ablative Therapies for Barrett’s Esophagus

Article

Abstract

Barrett’s esophagus has gained increased clinical attention because of its association with esophageal adenocarcinoma, a cancer with increasing incidence and poor survival rates. The goals of ablating Barrett’s esophagus are to decrease esophageal cancer rates and to improve overall survival and quality of life. Different techniques have been developed and tested for their effectiveness eradicating Barrett’s epithelium. This review assesses the literature associated with different ablative techniques. The safety and efficacy of different techniques are discussed. This review concludes with recommendations for the clinician, including specific strategies for patient care decisions for patients with Barrett’s esophagus with varying degrees of dysplasia.

Keywords

Ablation Argon plasma coagulation Barrett’s esophagus Cryotherapy Dysplasia Endoscopy Endoscopic mucosal resection Esophageal adenocarcinoma Photodynamic therapy Proton pump inhibitor Radiofrequency ablation 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Division of Gastroenterology, Institute for Genome Science and PolicyDuke UniversityDurhamUSA
  2. 2.Durham VA Medical CenterDurhamUSA
  3. 3.Center for Esophageal Diseases and SwallowingUniversity of North Carolina School of MedicineChapel HillUSA

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