Current Gastroenterology Reports

, Volume 13, Issue 2, pp 140–149 | Cite as

Recurrent and Relapsing Pancreatitis

  • Nalini M. GudaEmail author
  • Joseph Romagnuolo
  • Martin L. Freeman


Recurrent acute pancreatitis is a common clinical problem. Most cases of pancreatitis are identified by a careful history and physical examination. Despite advanced evaluation, the cause is not apparent in about 10% of cases. The etiology of recurrent acute pancreatitis appears to be multifactorial, with genetic and environmental influences playing a significant role. The strength of evidence for certain etiologies is highly variable, and natural history data are limited. Controversy exists regarding the most appropriate diagnostic and therapeutic approach. Recurrent acute pancreatitis often represents a continuum with chronic pancreatitis.


Pancreatitis Recurrent acute pancreatitis Idiopathic pancreatitis Endoscopic retrograde cholangiopancreatography Endoscopic ultrasound Magnetic resonance cholangiopancreatography 



Conflicts of interest: N.M. Guda—grant support, Cook, Inc.; J. Romagnuolo—consultancy, Olympus, grant support, Sanofi, Merck, Pfizer, NIH, ASGE, and CIHR, honoraria and speakers’ honoraria, Cook Endoscopy, and travel reimbursement, Epigenomics and Pfizer; and M.L. Freeman—honoraria, Boston Scientific and Cook, Inc.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Nalini M. Guda
    • 1
    Email author
  • Joseph Romagnuolo
    • 2
  • Martin L. Freeman
    • 3
    • 4
    • 5
    • 6
  1. 1.University of Wisconsin School of Medicine and Public HealthSt. Luke’s Medical CenterMilwaukeeUSA
  2. 2.Division of Gastroenterology and Hepatology, Digestive Disease CenterMedical University of South CarolinaCharlestonUSA
  3. 3.Division of Gastroenterology, Hepatology and NutritionUniversity of MinnesotaMinneapolisUSA
  4. 4.Total Pancreatectomy and Islet AutotransplantationUniversity of MinnesotaMinneapolisUSA
  5. 5.Pancreaticobiliary Endoscopy FellowshipUniversity of MinnesotaMinneapolisUSA
  6. 6.American Pancreatic AssociationUniversity of MinnesotaMinneapolisUSA

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