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Current Gastroenterology Reports

, Volume 10, Issue 1, pp 36–42 | Cite as

Live donor liver transplantation: Current status

  • Sonja K. Olsen
  • Robert S. BrownJr
Article

Abstract

The inequality between supply of grafts and demand for transplants has forced the transplant community to devise ways to increase the number of available livers for transplant (ie, through use of extended criteria donor grafts and living donation). Since 2002, the number of live donor liver transplantations (LDLT) performed has declined due to concerns of donor safety and lack of clear outcome data establishing success equivalent to that of deceased donor liver transplantation (DDLT). Recent data suggest that LDLT outcomes are comparable with those of DDLT, provided a center has performed more than 20 procedures, both in patients with and without hepatitis C. Further studies are needed to define the optimal donor and the ideal recipient for LDLT. Results from a National Institutes of Health-funded consortium of nine transplant centers are highly anticipated. These data are expected to underscore the viability of LDLT as a life-saving therapy for certain patients with end-stage liver disease.

Keywords

Graft Survival Live Donor Liver Transplantation Donor Liver Transplantation Milan Criterion Deceased Donor Liver Transplantation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  1. 1.Center for Liver Disease and Transplantation, New York-Presbyterian HospitalColumbia University College of Physicians and SurgeonsNew YorkUSA

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