Current Gastroenterology Reports

, Volume 8, Issue 5, pp 383–389 | Cite as

Extraintestinal manifestations of celiac disease

Article

Abstract

Celiac disease is an autoimmune disorder that occurs in genetically predisposed individuals as the result of an immune response to gluten. It is present in approximately 1% of the population. Diarrhea has become a less common mode of presentation (< 50% of cases) than it once was. Other presentations include iron-deficiency anemia, osteoporosis, dermatitis herpetiforme, and neurologic disorders, mainly peripheral neuropathy and ataxia. Arthritis is commonly found in patients with celiac disease when systematically sought. Overall, autoimmune diseases occur more frequently (three to ten times more) in those with celiac disease than in the general population. A gluten-free diet is the standard of treatment, although its effect on some of the extraintestinal manifestations remains to be determined.

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© Current Science Inc 2006

Authors and Affiliations

  1. 1.Columbia University College of Physicians and SurgeonsNew YorkUSA

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