Current Gastroenterology Reports

, Volume 2, Issue 3, pp 253–258

New developments in total parenteral nutrition for children

  • Robert J. Shulman

DOI: 10.1007/s11894-000-0069-x

Cite this article as:
Shulman, R.J. Curr Gastroenterol Rep (2000) 2: 253. doi:10.1007/s11894-000-0069-x


The field of parenteral nutrition continues to evolve along two major paths: prevention of complications and refining of nutritional needs. Parenteral nutrition-associated liver disease remains a vexing problem. No single factor is to blame; rather, it requires a number of “hits.” In the infant, the liver disease primarily appears to be related to prematurity of bile flow and production, infection, lack of enteral feedings, and most recently appreciated, perhaps free radicals. We are able to meet the nutritional needs of our patients, but our knowledge of actual nutritional requirements remains incomplete. Future studies need to define better appropriate intakes and to rigorously test the utility of proposed nutrients such as glutamine.

Copyright information

© Current Science Inc 2000

Authors and Affiliations

  • Robert J. Shulman
    • 1
  1. 1.USDA/ARS Children's Nutrition Research Center, Department of PediatricsBaylor College of Medicine and Texas Children's HospitalHoustonUSA

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