Sitting Less and Moving More: Improved Glycaemic Control for Type 2 Diabetes Prevention and Management
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Epidemiological evidence indicates that excessive time spent in sedentary behaviours (too much sitting) is associated with an increased risk of type 2 diabetes (T2D). Here, we highlight findings of experimental studies corroborating and extending the epidemiological evidence and showing the potential benefits for T2D of reducing and breaking up sitting time across the whole day. We also discuss future research opportunities and consider emerging implications for T2D prevention and management. This new evidence is stimulating an expansion of diabetes-related physical activity guidelines—suggesting that in addition to moderate-vigorous physical activity, reducing and regularly interrupting prolonged sitting time is likely to have important and varied benefits across the spectrum of diabetes risk.
KeywordsSitting Sedentary behaviour Breaks in sedentary time Physical activity Exercise Diabetes Insulin resistance Metabolic syndrome Prediabetes Glycaemic control Cardiovascular Cardiometabolic risk
Neville Owen is supported by a NHMRC Program Grant (#569940) and a NHMRC Senior Principal Research Fellowship (#1003960) and the Victorian Government’s Operational Infrastructure Support Program. Thomas E. Yates helped develop and validate a diabetes prevention programme, Let’s Prevent Diabetes, selected to be part of Healthier You: The NHS Diabetes Prevention Programme in collaboration with Ingeus UK Limited. Bronwyn A. Kingwell is supported by a NHMRC Program Grant (#1036352) and a NHMRC Senior Principal Research Fellowship (#1059454) and the Victorian Government’s Operational Infrastructure Support Program. David W. Dunstan is supported by an NHMRC Senior Research Fellowship (#1078360) and the Victorian Government’s Operational Infrastructure Support Program and was invited keynote presenter at the 2nd Annual JustStand Wellness Summit in July 2012. His travel and housing expenses were covered by Ergotron Pty Ltd. No honorarium was received.
Compliance with Ethical Standards
Conflict of Interest
Paddy C. Dempsey, Neville Owen, Thomas E. Yates, Bronwyn A. Kingwell and David W. Dunstan declare that they have no conflicts of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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