Current Diabetes Reports

, Volume 12, Issue 3, pp 286–293 | Cite as

Diagnosis of Coronary Artery Disease in Persons with Diabetes Mellitus

Management of Macrovascular Disease in Diabetes (S Inzucchi and R Goldberg, Section Editors)


Coronary heart disease (CHD) is the leading cause of morbidity and mortality in patients with diabetes. Asymptomatic CHD in these patients is elusive and carries a poor prognosis given the fact that an unheralded acute myocardial infarction or sudden cardiac death frequently constitutes its first presentation. Because effective screening for asymptomatic patients with type 2 diabetes for both the presence and severity of CHD is intuitively appealing, we have summarized the utility and prognostic value of various diagnostic modalities (both functionally and anatomically) in enhancing risk stratification and leading to improved and more aggressive management of the risk factors. There exist some evidence and recommendations for screening of asymptomatic persons with diabetes using certain modalities. More research is needed to define potential subsets of patients with diabetes who may benefit from additional testing for asymptomatic CHD.


Risk assessment Cardiac testing Coronary artery disease Diabetes 



Conflicts of interest: N. Alipour: no disclosures; N. Wong: research support from Bristol Myers-Squibb and Merck through the University of California, Irvine; S. Malik: has received grant support from the National Heart, Lung, and Blood Institute.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Cardiology, Department of MedicineUniversity of California, IrvineOrangeUSA

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