Alternative and Complementary Treatments for Metabolic Syndrome
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Metabolic syndrome is defined by a cluster of cardiovascular disease risk factors that are associated with insulin resistance. In recent years, a number of innovative nutritional strategies have been proposed as safe alternative treatments to reduce the morbidity as well as the cost of treating metabolic syndrome. Of these, dietary supplementation with chromium picolinate or cinnamon extract has been studied most extensively. These interventions may attenuate insulin resistance and reduce the cardiovascular risk factors that together comprise the metabolic syndrome. However, more clinical trials are needed to determine the dose and duration of such treatments to make specific recommendations for populations with metabolic syndrome.
KeywordsMetabolic syndrome Chromium Cinnamon Insulin resistance
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- 2.Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adults Treatment Panel III) [no authors listed]. JAMA 2001, 285:2486–2497.Google Scholar
- 8.National Research Counsil, Food and Nutrition Board. Recommended dietary allowances. 10th ed. Washington: National Academy Press; 1989.Google Scholar
- 12.Offenbacher EG. Promotion of chromium absorptionby ascorbic acid. Trace Elem Electrolytes. 1994;11:178.Google Scholar
- 24.Gunton JE, Cheung NW, Hitchman R, et al. Chromium supplementation does not improve glucose tolerance, insulin sensitivity, or lipid profile: a randomized, placebo-controlled, double-blind trial of supplementation in subjects with impaired glucose tolerance. Diab Care. 2005;28:712–3.CrossRefGoogle Scholar
- 27.Iqbal N, Cardillo S, Volger S, et al.: Chromium Picolinate Does Not Improve Key Features of Metabolic Syndrome in Obese Nondiabetic Adults. Metab Syndr Relat Disord 2009.Google Scholar
- 43.• Crawford P: Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009, 22:507–512. This is a recent clinical trial demonstrating positive effect of cinnamon extract on HbA 1c levels in people with type 2 diabetes.PubMedCrossRefGoogle Scholar
- 45.Feiner JJ, McNurlan MA, Ferris RE, et al. Chromium picolinate for insulin resistance in subjects with HIV disease: a pilot study. Diab Obes Metab. 2008;10:151–8.Google Scholar