Current Diabetes Reports

, Volume 6, Issue 6, pp 463–468 | Cite as

Inflammation and diabetic nephropathy

  • Carmen Mora
  • Juan F. Navarro


Diabetic nephropathy has become the main cause of renal failure, but unfortunately the intimate mechanisms leading to the development and progression of renal injury are not yet fully known. Activated innate immunity and inflammation are relevant factors in the pathogenesis of diabetes. Moreover, different inflammatory molecules, including chemokines, adhesion molecules, and proinflammatory cytokines, may be critical factors in the development of microvascular diabetic complications, including nephropathy. This new pathogenic perspective leads to important therapeutic considerations, with new pathogenic pathways becoming important therapeutic targets that can be translated into clinical treatments for diabetic nephropathy.


Diabetic Nephropathy Renal Injury Pentoxifylline Urinary Albumin Excretion European Prospective Investigation Into Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Current Science Inc 2006

Authors and Affiliations

  1. 1.Nephrology ServiceUniversity Hospital Nuestra Señora de CandelariaSanta Cruz de TenerifeSpain

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