Current Diabetes Reports

, Volume 6, Issue 6, pp 455–462

Lipids and diabetic nephropathy

Article

DOI: 10.1007/s11892-006-0079-7

Cite this article as:
Rosario, R.F. & Prabhakar, S. Curr Diab Rep (2006) 6: 455. doi:10.1007/s11892-006-0079-7

Abstract

Although several factors may mediate the development and progression of diabetic nephropathy, hyperlipidemia is now considered an independent and major determinant of progression of renal disease in diabetes. The following discussion focuses on the experimental evidence that incriminates hyperlipidemia as a pathogenic factor for diabetic nephropathy and the potential mechanisms that may mediate renal injury from hyperlipidemia, as well as the clinical studies involving therapeutic interventions for hyperlipidemia and their impact on progression of diabetic renal disease.

Copyright information

© Current Science Inc 2006

Authors and Affiliations

  1. 1.Division of Nephrology Department of Medicine and PhysiologyTexas Tech University Health Sciences CenterLubbockUSA

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